Clinical Trials

{
  "url": "https://clinicaltrials.gov/study/NCT07620015",
  "title": "Turkish Version of the Ankle Fracture Outcome of Rehabilitation Measure (A-FORM-TR): A Multi-Centre Validation Study",
  "nct_id": "NCT07620015",
  "phases": [],
  "source": "clinicaltrials.gov",
  "status": "RECRUITING",
  "conditions": [
    "Ankle Fractures",
    "Ankle Injuries"
  ],
  "enrollment": 150,
  "study_type": "OBSERVATIONAL",
  "lead_sponsor": "Utku Gürhan",
  "published_at": "2026-07-27T00:00:00.000Z",
  "interventions": [],
  "sponsor_class": "OTHER",
  "official_title": "Cross-Cultural Adaptation and Psychometric Validation of the Turkish Version of the Ankle Fracture Outcome of Rehabilitation Measure (A-FORM-TR): A Multi-Centre Prospective Observational Study",
  "first_posted_at": "2026-06-02T00:00:00.000Z"
}

{
  "url": "https://clinicaltrials.gov/study/NCT05556824",
  "title": "Multi-Center Study of Panosyl-Isomaltooligosaccharides Adjunctive to PPI Therapy to Treat GERD",
  "nct_id": "NCT05556824",
  "phases": [
    "PHASE2"
  ],
  "source": "clinicaltrials.gov",
  "status": "COMPLETED",
  "conditions": [
    "Gastroesophageal Reflux"
  ],
  "enrollment": 255,
  "study_type": "INTERVENTIONAL",
  "lead_sponsor": "Microbiome Health Sciences",
  "published_at": "2026-07-27T00:00:00.000Z",
  "interventions": [
    {
      "name": "MHS-1031",
      "type": "DRUG"
    },
    {
      "name": "Placebo",
      "type": "OTHER"
    }
  ],
  "sponsor_class": "INDUSTRY",
  "official_title": "A Multi-Center Study of Panosyl-Isomaltooligosaccharides (PIMO) Adjunctive to Proton Pump Inhibitor (PPI) Therapy to Treat Gastroesophageal Reflux Disease (GERD) in Subjects Who Are PPI-Responders or PPI-Partial Responders",
  "first_posted_at": "2022-09-27T00:00:00.000Z"
}

{
  "url": "https://clinicaltrials.gov/study/NCT04041713",
  "title": "A Pilot Study of an Antioxidant Cocktail vs. Placebo in the Treatment of Children and Adolescents With Rett Syndrome",
  "nct_id": "NCT04041713",
  "phases": [
    "PHASE2"
  ],
  "source": "clinicaltrials.gov",
  "status": "NOT_YET_RECRUITING",
  "conditions": [
    "Rett Syndrome"
  ],
  "enrollment": 35,
  "study_type": "INTERVENTIONAL",
  "lead_sponsor": "Holland Bloorview Kids Rehabilitation Hospital",
  "published_at": "2026-07-27T00:00:00.000Z",
  "interventions": [
    {
      "name": "Rett-T",
      "type": "DRUG"
    },
    {
      "name": "Placebo",
      "type": "OTHER"
    }
  ],
  "sponsor_class": "OTHER",
  "official_title": "A Pilot Study of an Antioxidant Cocktail vs. Placebo in the Treatment of Children and Adolescents With Rett Syndrome",
  "first_posted_at": "2019-08-01T00:00:00.000Z"
}

{
  "url": "https://clinicaltrials.gov/study/NCT07727980",
  "title": "Tissue Preservation in Immediate 1C Implants Using an Anatomical Prefabricated Healing Abutment",
  "nct_id": "NCT07727980",
  "phases": [
    "NA"
  ],
  "source": "clinicaltrials.gov",
  "status": "NOT_YET_RECRUITING",
  "conditions": [
    "Tooth Loss",
    "Dental Implant",
    "Clinical Trials",
    "Randomized Controlled Trial",
    "Immediate Dental Implant Placement",
    "Molar Extraction Socket",
    "Maxilla",
    "MANDIBLE"
  ],
  "enrollment": 30,
  "study_type": "INTERVENTIONAL",
  "lead_sponsor": "University of Illinois at Chicago",
  "published_at": "2026-07-27T00:00:00.000Z",
  "interventions": [
    {
      "name": "scannable anatomical healing abutment",
      "type": "DEVICE"
    },
    {
      "name": "Standard Healing Abutment for Dental Implants",
      "type": "DEVICE"
    }
  ],
  "sponsor_class": "OTHER",
  "official_title": "Tissue Preservation in Immediate 1C Implants Using an Anatomical Prefabricated Healing Abutment",
  "first_posted_at": "2026-07-27T00:00:00.000Z"
}

{
  "url": "https://clinicaltrials.gov/study/NCT07728318",
  "title": "Efficacy, Safety, and Treatment Satisfaction of Once-Weekly Tirzepatide in Obese Type 2 Diabetic Patients",
  "nct_id": "NCT07728318",
  "phases": [
    "NA"
  ],
  "source": "clinicaltrials.gov",
  "status": "NOT_YET_RECRUITING",
  "conditions": [
    "Type 2 Diabetes Mellitus (T2DM), Obesity, Overweight"
  ],
  "enrollment": 52,
  "study_type": "INTERVENTIONAL",
  "lead_sponsor": "Akhtar Saeed Medical and Dental College",
  "published_at": "2026-07-27T00:00:00.000Z",
  "interventions": [
    {
      "name": "Tirzepatide + Standard Therapy (Intervention Group)",
      "type": "OTHER"
    },
    {
      "name": "Standard Oral Antidiabetic Drugs (OADs)",
      "type": "OTHER"
    }
  ],
  "sponsor_class": "OTHER",
  "official_title": "Efficacy, Safety and Treatment Satisfaction of Once Weekly Tirzepatide in Obese Type 2 Diabetic Patients at a Tertiary Care Centre",
  "first_posted_at": "2026-07-27T00:00:00.000Z"
}

{
  "url": "https://clinicaltrials.gov/study/NCT04898790",
  "title": "Improving Cognitive Function in Older Adults Undergoing Stem Cell Transplant",
  "nct_id": "NCT04898790",
  "phases": [
    "NA"
  ],
  "source": "clinicaltrials.gov",
  "status": "RECRUITING",
  "conditions": [
    "Leukemia",
    "Lymphoma",
    "Multiple Myeloma",
    "Myelodysplastic Syndromes (MDS)",
    "Myeloproliferative Neoplasm"
  ],
  "enrollment": 108,
  "study_type": "INTERVENTIONAL",
  "lead_sponsor": "University of Nebraska",
  "published_at": "2026-07-27T00:00:00.000Z",
  "interventions": [
    {
      "name": "CHAMPS-II adapted to adults 60+ years in HCT setting",
      "type": "BEHAVIORAL"
    }
  ],
  "sponsor_class": "OTHER",
  "official_title": "Promoting Physical Activity to Improve Cognitive Function in Older Adults Undergoing Hematopoietic Cell Transplantation",
  "first_posted_at": "2021-05-24T00:00:00.000Z"
}

{
  "url": "https://clinicaltrials.gov/study/NCT01810913",
  "title": "Testing Docetaxel-Cetuximab or the Addition of an Immunotherapy Drug, Atezolizumab, to the Usual Chemotherapy and Radiation Therapy in High-Risk Head and Neck Cancer",
  "nct_id": "NCT01810913",
  "phases": [
    "PHASE2",
    "PHASE3"
  ],
  "source": "clinicaltrials.gov",
  "status": "SUSPENDED",
  "conditions": [
    "Oropharyngeal p16INK4a-Negative Squamous Cell Carcinoma",
    "Stage III Hypopharyngeal Squamous Cell Carcinoma AJCC v7",
    "Stage III Laryngeal Squamous Cell Carcinoma AJCC v6 and v7",
    "Stage III Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7",
    "Stage III Oropharyngeal Squamous Cell Carcinoma AJCC v7",
    "Stage IV Hypopharyngeal Squamous Cell Carcinoma AJCC v7",
    "Stage IV Laryngeal Squamous Cell Carcinoma AJCC v7",
    "Stage IV Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7",
    "Stage IV Oropharyngeal Squamous Cell Carcinoma AJCC v7"
  ],
  "enrollment": 613,
  "study_type": "INTERVENTIONAL",
  "lead_sponsor": "National Cancer Institute (NCI)",
  "published_at": "2026-07-27T00:00:00.000Z",
  "interventions": [
    {
      "name": "Atezolizumab",
      "type": "DRUG"
    },
    {
      "name": "Biopsy Procedure",
      "type": "PROCEDURE"
    },
    {
      "name": "Biospecimen Collection",
      "type": "PROCEDURE"
    },
    {
      "name": "Cetuximab",
      "type": "BIOLOGICAL"
    },
    {
      "name": "Cisplatin",
      "type": "DRUG"
    },
    {
      "name": "Computed Tomography",
      "type": "PROCEDURE"
    },
    {
      "name": "Docetaxel",
      "type": "DRUG"
    },
    {
      "name": "Intensity-Modulated Radiation Therapy",
      "type": "RADIATION"
    },
    {
      "name": "Magnetic Resonance Imaging",
      "type": "PROCEDURE"
    },
    {
      "name": "Survey Administration",
      "type": "OTHER"
    }
  ],
  "sponsor_class": "NIH",
  "official_title": "Randomized Phase II/III Trial of Adjuvant Radiation Therapy With Cisplatin, Docetaxel-Cetuximab, or Cisplatin-Atezolizumab in Pathologic High-Risk Squamous Cell Cancer of the Head and Neck",
  "first_posted_at": "2013-03-14T00:00:00.000Z"
}

{
  "url": "https://clinicaltrials.gov/study/NCT07513207",
  "title": "A Study in Healthy People to Test How Vicadrostat Affects the Heart",
  "nct_id": "NCT07513207",
  "phases": [
    "PHASE1"
  ],
  "source": "clinicaltrials.gov",
  "status": "ACTIVE_NOT_RECRUITING",
  "conditions": [
    "Healthy"
  ],
  "enrollment": 45,
  "study_type": "INTERVENTIONAL",
  "lead_sponsor": "Boehringer Ingelheim",
  "published_at": "2026-07-27T00:00:00.000Z",
  "interventions": [
    {
      "name": "Vicadrostat",
      "type": "DRUG"
    },
    {
      "name": "Placebo matching Vicadrostat",
      "type": "DRUG"
    },
    {
      "name": "Moxifloxacin",
      "type": "DRUG"
    }
  ],
  "sponsor_class": "INDUSTRY",
  "official_title": "Thorough QT Study to Evaluate the Effects of Single Doses of Vicadrostat on Cardiac Safety Parameters in Healthy Male and Female Subjects (a Randomized, Placebo-controlled, Double-blind, Five-period Crossover Study With Open-label Moxifloxacin as Positive Control)",
  "first_posted_at": "2026-04-07T00:00:00.000Z"
}

{
  "url": "https://clinicaltrials.gov/study/NCT07724457",
  "title": "Testing the Addition of a New Anti-Cancer Drug, Glofitamab to Usual Chemotherapy for Burkitt and Double Hit Lymphoma",
  "nct_id": "NCT07724457",
  "phases": [
    "PHASE2",
    "PHASE3"
  ],
  "source": "clinicaltrials.gov",
  "status": "NOT_YET_RECRUITING",
  "conditions": [
    "Recurrent Burkitt Lymphoma",
    "Recurrent High Grade B-Cell Lymphoma With MYC and BCL2 Rearrangements",
    "Refractory Burkitt Lymphoma",
    "Refractory High Grade B-Cell Lymphoma With MYC and BCL2 Rearrangements"
  ],
  "enrollment": 271,
  "study_type": "INTERVENTIONAL",
  "lead_sponsor": "National Cancer Institute (NCI)",
  "published_at": "2026-07-27T00:00:00.000Z",
  "interventions": [
    {
      "name": "Biospecimen Collection",
      "type": "PROCEDURE"
    },
    {
      "name": "Bone Marrow Biopsy",
      "type": "PROCEDURE"
    },
    {
      "name": "Carboplatin",
      "type": "DRUG"
    },
    {
      "name": "Computed Tomography",
      "type": "PROCEDURE"
    },
    {
      "name": "Cyclophosphamide",
      "type": "DRUG"
    },
    {
      "name": "Cytarabine",
      "type": "DRUG"
    },
    {
      "name": "Doxorubicin",
      "type": "DRUG"
    },
    {
      "name": "Etoposide",
      "type": "DRUG"
    },
    {
      "name": "Glofitamab",
      "type": "BIOLOGICAL"
    },
    {
      "name": "Ifosfamide",
      "type": "DRUG"
    }
  ],
  "sponsor_class": "NIH",
  "official_title": "A Randomized Phase 2/3 Study the Bispecific Antibody (BsAb), Glofitamab, Plus Chemoimmunotherapy in Newly Diagnosed and Relapsed Burkitt and High-Grade (Double Hit) B-Cell Lymphomas With MYC and BCL2 Rearrangements",
  "first_posted_at": "2026-07-24T00:00:00.000Z"
}

{
  "url": "https://clinicaltrials.gov/study/NCT05318521",
  "title": "RCT, Blinded, 2-Arm Efficacy Study of IP and Placebo in Patients With Chronic Pain Related to Osteoarthritis of the Knee",
  "nct_id": "NCT05318521",
  "phases": [
    "PHASE3"
  ],
  "source": "clinicaltrials.gov",
  "status": "ACTIVE_NOT_RECRUITING",
  "conditions": [
    "Degenerative Arthritis"
  ],
  "enrollment": 500,
  "study_type": "INTERVENTIONAL",
  "lead_sponsor": "Overseas Pharmaceuticals, Ltd.",
  "published_at": "2026-07-27T00:00:00.000Z",
  "interventions": [
    {
      "name": "Placebo",
      "type": "DRUG"
    },
    {
      "name": "Ibuprofen modified release tablet 800 mg",
      "type": "DRUG"
    }
  ],
  "sponsor_class": "INDUSTRY",
  "official_title": "A Randomized, Double-Blind, Parallel-Arm Study Comparing the Efficacy of Investigational Product \"Ibuprofen Modified-Release Tablets 800 mg\" and Placebo in Patients With Chronic Pain Related to Osteoarthritis of the Knee",
  "first_posted_at": "2022-04-08T00:00:00.000Z"
}