Clinical Trials

{
  "url": "https://clinicaltrials.gov/study/NCT02877394",
  "title": "Use of a Squatting Assist Device in Patients With Constipation",
  "nct_id": "NCT02877394",
  "phases": [
    "PHASE2"
  ],
  "source": "clinicaltrials.gov",
  "status": "ACTIVE_NOT_RECRUITING",
  "conditions": [
    "Constipation"
  ],
  "enrollment": 107,
  "study_type": "INTERVENTIONAL",
  "lead_sponsor": "Mayo Clinic",
  "published_at": "2026-07-28T00:00:00.000Z",
  "interventions": [
    {
      "name": "Squatting Assist Device",
      "type": "DEVICE"
    },
    {
      "name": "Sham Squatting Assist Device",
      "type": "DEVICE"
    }
  ],
  "sponsor_class": "OTHER",
  "official_title": "Use of a Squatting Assist Device in Patients With Constipation",
  "first_posted_at": "2016-08-24T00:00:00.000Z"
}

{
  "url": "https://clinicaltrials.gov/study/NCT05642195",
  "title": "Evaluation of a Cancer Lysate Vaccine and Montanide (Registered Trademark) ISA-51 VG With or Without the IL-15 Super-Agonist N-803 as Adjuvant Therapy for PD-L1 Negative Non-Small Cell Lung Cancer",
  "nct_id": "NCT05642195",
  "phases": [
    "PHASE1",
    "PHASE2"
  ],
  "source": "clinicaltrials.gov",
  "status": "SUSPENDED",
  "conditions": [
    "Non-Small Cell Lung Cancer",
    "Non-Small Cell Lung Carcinoma",
    "Carcinoma, Non-Small-Cell Lung",
    "Carcinomas"
  ],
  "enrollment": 30,
  "study_type": "INTERVENTIONAL",
  "lead_sponsor": "National Cancer Institute (NCI)",
  "published_at": "2026-07-28T00:00:00.000Z",
  "interventions": [
    {
      "name": "Montanide (Registered Trademark) ISA-51 VG Adjuvant",
      "type": "BIOLOGICAL"
    },
    {
      "name": "H1299 Cell Lysates",
      "type": "BIOLOGICAL"
    },
    {
      "name": "N-803",
      "type": "DRUG"
    },
    {
      "name": "Ventana PD-L1 (SP263 or SP142) assay",
      "type": "DEVICE"
    }
  ],
  "sponsor_class": "NIH",
  "official_title": "Phase I/II Evaluation of a Cancer Lysate Vaccine and Montanide(R) ISA-51 VG With or Without the IL-15 Super-Agonist N-803 as Adjuvant Therapy for PD-L1 Negative Non-Small Cell Lung Cancer",
  "first_posted_at": "2022-12-08T00:00:00.000Z"
}

{
  "url": "https://clinicaltrials.gov/study/NCT07729761",
  "title": "Impact of Instability Training on Vestibular Dysfunction in Postconcussion Combat Athletes",
  "nct_id": "NCT07729761",
  "phases": [
    "NA"
  ],
  "source": "clinicaltrials.gov",
  "status": "COMPLETED",
  "conditions": [
    "Concussion, Mild"
  ],
  "enrollment": 36,
  "study_type": "INTERVENTIONAL",
  "lead_sponsor": "Riphah International University",
  "published_at": "2026-07-28T00:00:00.000Z",
  "interventions": [
    {
      "name": "Traditional Physical therapy",
      "type": "OTHER"
    },
    {
      "name": "Instability training",
      "type": "OTHER"
    }
  ],
  "sponsor_class": "OTHER",
  "official_title": "Effects of Instability Training on Vestibular Impairment in Post Concussion Combat Athletes",
  "first_posted_at": "2026-07-28T00:00:00.000Z"
}

{
  "url": "https://clinicaltrials.gov/study/NCT07731659",
  "title": "Physical Activity Intervention for Individuals Newly Diagnosed With MS",
  "nct_id": "NCT07731659",
  "phases": [
    "NA"
  ],
  "source": "clinicaltrials.gov",
  "status": "NOT_YET_RECRUITING",
  "conditions": [
    "Multiple Sclerosis"
  ],
  "enrollment": 50,
  "study_type": "INTERVENTIONAL",
  "lead_sponsor": "University of Illinois at Chicago",
  "published_at": "2026-07-28T00:00:00.000Z",
  "interventions": [
    {
      "name": "COM-B-based Physical Activity Behavior Change Intervention",
      "type": "BEHAVIORAL"
    }
  ],
  "sponsor_class": "OTHER",
  "official_title": "Physical Activity Behavior Change Intervention in Persons Newly Diagnosed With Multiple Sclerosis - ActivNMS Trial - COM-B Construct Testing",
  "first_posted_at": "2026-07-28T00:00:00.000Z"
}

{
  "url": "https://clinicaltrials.gov/study/NCT07715903",
  "title": "Hepatic Artery Infusion of Carfilzomib in Participants With Liver Metastatic Disease Previously Treated With Hepatic Artery Infusion Pump Therapy",
  "nct_id": "NCT07715903",
  "phases": [
    "PHASE1"
  ],
  "source": "clinicaltrials.gov",
  "status": "NOT_YET_RECRUITING",
  "conditions": [
    "Colorectal Neoplasms",
    "Neoplasms",
    "Intrahepatic Cholangiocarcinoma",
    "Adrenocortical Carcinoma",
    "Metastasis, Neoplasm"
  ],
  "enrollment": 20,
  "study_type": "INTERVENTIONAL",
  "lead_sponsor": "National Cancer Institute (NCI)",
  "published_at": "2026-07-28T00:00:00.000Z",
  "interventions": [
    {
      "name": "Carfilzomib",
      "type": "DRUG"
    }
  ],
  "sponsor_class": "NIH",
  "official_title": "Phase I Study Evaluating Hepatic Artery Infusion of Carfilzomib in Participants With Liver Metastatic Disease Previously Treated With Hepatic Artery Infusion Pump Therapy",
  "first_posted_at": "2026-07-21T00:00:00.000Z"
}

{
  "url": "https://clinicaltrials.gov/study/NCT07730151",
  "title": "Efficacy and Safety of Darolutamide Combined With Docetaxel and ADT as Neoadjuvant Therapy for Locally Advanced Prostate Cancer.",
  "nct_id": "NCT07730151",
  "phases": [
    "PHASE2"
  ],
  "source": "clinicaltrials.gov",
  "status": "NOT_YET_RECRUITING",
  "conditions": [
    "Prostate Cancer",
    "Prostate",
    "Prostate Cancer Patients"
  ],
  "enrollment": 200,
  "study_type": "INTERVENTIONAL",
  "lead_sponsor": "RenJi Hospital",
  "published_at": "2026-07-28T00:00:00.000Z",
  "interventions": [
    {
      "name": "Darolutamide",
      "type": "DRUG"
    },
    {
      "name": "docetaxel",
      "type": "DRUG"
    },
    {
      "name": "ADT",
      "type": "DRUG"
    }
  ],
  "sponsor_class": "OTHER",
  "official_title": "Efficacy and Safety of Darolutamide Combined With Docetaxel and ADT as Neoadjuvant Therapy for Locally Advanced Prostate Cancer: A Multicenter, Prospective, Randomized Controlled Study",
  "first_posted_at": "2026-07-28T00:00:00.000Z"
}

{
  "url": "https://clinicaltrials.gov/study/NCT07633288",
  "title": "A Clinical Trial Evaluating the Safety and Efficacy of AP1189 Versus Placebo as an add-on to Standard of Care in Participants With Respiratory Insufficiency Expected to be Caused by Infection With Respiratory Viruses",
  "nct_id": "NCT07633288",
  "phases": [
    "PHASE2"
  ],
  "source": "clinicaltrials.gov",
  "status": "RECRUITING",
  "conditions": [
    "Respiratory Viral Infection"
  ],
  "enrollment": 96,
  "study_type": "INTERVENTIONAL",
  "lead_sponsor": "SynAct Pharma Aps",
  "published_at": "2026-07-28T00:00:00.000Z",
  "interventions": [
    {
      "name": "AP1189, 100 mg",
      "type": "DRUG"
    },
    {
      "name": "Placebo",
      "type": "DRUG"
    }
  ],
  "sponsor_class": "INDUSTRY",
  "official_title": "A Randomized, Double-blind, Multicentre, Placebo-controlled, Proof-of-concept Clinical Trial Evaluating the Safety and Efficacy of the Biased Melanocortin Agonist AP1189 Versus Placebo as an add-on to Standard of Care (SOC) in Participants With RESPIRatory Insufficiency Expected to be Caused by Infection With Respiratory Viruses, Including Influenza, Respiratory Syncytial Virus, and Coronavirus",
  "first_posted_at": "2026-06-08T00:00:00.000Z"
}

{
  "url": "https://clinicaltrials.gov/study/NCT07059494",
  "title": "Atezolizumab and Bevacizumab in Combination With Y^90 Radioembolization in HCC for Liver Transplant",
  "nct_id": "NCT07059494",
  "phases": [
    "PHASE4"
  ],
  "source": "clinicaltrials.gov",
  "status": "RECRUITING",
  "conditions": [
    "Hepatocellular Carcinoma"
  ],
  "enrollment": 40,
  "study_type": "INTERVENTIONAL",
  "lead_sponsor": "Icahn School of Medicine at Mount Sinai",
  "published_at": "2026-07-28T00:00:00.000Z",
  "interventions": [
    {
      "name": "Atezolizumab",
      "type": "DRUG"
    },
    {
      "name": "Bevacizumab",
      "type": "DRUG"
    },
    {
      "name": "Y^90 Radioembolization",
      "type": "RADIATION"
    }
  ],
  "sponsor_class": "OTHER",
  "official_title": "A Feasibility Clinical Trial of Atezolizumab and Bevacizumab in Combination With Y^90 Radioembolization for Patients With Hepatocellular Carcinoma (HCC) for Liver Transplantation",
  "first_posted_at": "2025-07-10T00:00:00.000Z"
}

{
  "url": "https://clinicaltrials.gov/study/NCT00067054",
  "title": "Apheresis and Specimen Collection Procedures to Obtain Plasma, Peripheral Blood Mononuclear Cells (PBMCs) and Other Specimens for Research Studies",
  "nct_id": "NCT00067054",
  "phases": [],
  "source": "clinicaltrials.gov",
  "status": "RECRUITING",
  "conditions": [
    "Sample Collection"
  ],
  "enrollment": 3000,
  "study_type": "OBSERVATIONAL",
  "lead_sponsor": "National Institute of Allergy and Infectious Diseases (NIAID)",
  "published_at": "2026-07-28T00:00:00.000Z",
  "interventions": [],
  "sponsor_class": "NIH",
  "official_title": "VRC 200: A Multicenter Specimen Collection Protocol to Obtain Human Biological Samples for Research Studies",
  "first_posted_at": "2003-08-11T00:00:00.000Z"
}

{
  "url": "https://clinicaltrials.gov/study/NCT06767124",
  "title": "Supplementing Neuro-Energy to Aid Cognition",
  "nct_id": "NCT06767124",
  "phases": [
    "NA"
  ],
  "source": "clinicaltrials.gov",
  "status": "NOT_YET_RECRUITING",
  "conditions": [
    "Alzheimer Disease and Related Dementias (ADRD)"
  ],
  "enrollment": 17,
  "study_type": "INTERVENTIONAL",
  "lead_sponsor": "University of Pennsylvania",
  "published_at": "2026-07-28T00:00:00.000Z",
  "interventions": [
    {
      "name": "Ketogenic Supplement",
      "type": "DIETARY_SUPPLEMENT"
    },
    {
      "name": "Placebo Drink",
      "type": "OTHER"
    }
  ],
  "sponsor_class": "OTHER",
  "official_title": "Simultaneous PET/MR Imaging of Brain Glucose and Oxygen Metabolism to Assess Energy Deficits Related to Alzheimer's Disease and the Response to Intervention",
  "first_posted_at": "2025-01-09T00:00:00.000Z"
}