Clinical Trials

{
  "url": "https://clinicaltrials.gov/study/NCT07728175",
  "title": "Effects of Sirolimus on Asymptomatic ApoE4 Carriers",
  "nct_id": "NCT07728175",
  "phases": [
    "PHASE1"
  ],
  "source": "clinicaltrials.gov",
  "status": "NOT_YET_RECRUITING",
  "conditions": [
    "Genetic Predisposition to Disease",
    "Healthy Volunteer",
    "APOE-4 Positive"
  ],
  "enrollment": 225,
  "study_type": "INTERVENTIONAL",
  "lead_sponsor": "University of Missouri-Columbia",
  "published_at": "2026-07-29T00:00:00.000Z",
  "interventions": [
    {
      "name": "Sirolimus (rapamycin)",
      "type": "DRUG"
    },
    {
      "name": "Placebo",
      "type": "DRUG"
    }
  ],
  "sponsor_class": "OTHER",
  "official_title": "Effects of Sirolimus on Middle Aged Asymptomatic ApoE4 Carriers",
  "first_posted_at": "2026-07-27T00:00:00.000Z"
}

{
  "url": "https://clinicaltrials.gov/study/NCT05856994",
  "title": "Clinical Assessment of Protopic® Ointment in Deep Partial-Thickness Burns",
  "nct_id": "NCT05856994",
  "phases": [
    "PHASE1"
  ],
  "source": "clinicaltrials.gov",
  "status": "TERMINATED",
  "conditions": [
    "Burn Injury"
  ],
  "enrollment": 1,
  "study_type": "INTERVENTIONAL",
  "lead_sponsor": "Vanderbilt University Medical Center",
  "published_at": "2026-07-29T00:00:00.000Z",
  "interventions": [
    {
      "name": "Tacrolimus ointment",
      "type": "DRUG"
    }
  ],
  "sponsor_class": "OTHER",
  "official_title": "Clinical Assessment of Protopic® Ointment in Deep Partial-Thickness Burns",
  "first_posted_at": "2023-05-12T00:00:00.000Z"
}

{
  "url": "https://clinicaltrials.gov/study/NCT04808427",
  "title": "Pilot Study to Investigate Magnetic Resonance (MR) Image Guided Focal Therapy in Prostate Cancer",
  "nct_id": "NCT04808427",
  "phases": [
    "NA"
  ],
  "source": "clinicaltrials.gov",
  "status": "SUSPENDED",
  "conditions": [
    "Prostate Cancer"
  ],
  "enrollment": 21,
  "study_type": "INTERVENTIONAL",
  "lead_sponsor": "National Cancer Institute (NCI)",
  "published_at": "2026-07-29T00:00:00.000Z",
  "interventions": [
    {
      "name": "TULSA-PRO",
      "type": "DEVICE"
    }
  ],
  "sponsor_class": "NIH",
  "official_title": "Magnetic Resonance Image (MRI) Guided High Energy Ultrasound for Focal Prostate Cancer Ablation",
  "first_posted_at": "2021-03-22T00:00:00.000Z"
}

{
  "url": "https://clinicaltrials.gov/study/NCT07733882",
  "title": "Study on Clinical and Pathological Features of Primary Biliary Cholangitis and Risk Factors Related to Disease Progression",
  "nct_id": "NCT07733882",
  "phases": [],
  "source": "clinicaltrials.gov",
  "status": "NOT_YET_RECRUITING",
  "conditions": [
    "PBC"
  ],
  "enrollment": 300,
  "study_type": "OBSERVATIONAL",
  "lead_sponsor": "Beijing Municipal Administration of Hospitals",
  "published_at": "2026-07-29T00:00:00.000Z",
  "interventions": [],
  "sponsor_class": "OTHER_GOV",
  "official_title": "原发性胆汁性胆管炎临床、病理特征及病情进展相关危险因素研究",
  "first_posted_at": "2026-07-29T00:00:00.000Z"
}

{
  "url": "https://clinicaltrials.gov/study/NCT06910813",
  "title": "DFT383 in Pediatric Participants With Nephropathic Cystinosis",
  "nct_id": "NCT06910813",
  "phases": [
    "PHASE1",
    "PHASE2"
  ],
  "source": "clinicaltrials.gov",
  "status": "RECRUITING",
  "conditions": [
    "Nephropathic Cystinosis"
  ],
  "enrollment": 30,
  "study_type": "INTERVENTIONAL",
  "lead_sponsor": "Novartis Pharmaceuticals",
  "published_at": "2026-07-29T00:00:00.000Z",
  "interventions": [
    {
      "name": "DFT383",
      "type": "GENETIC"
    }
  ],
  "sponsor_class": "INDUSTRY",
  "official_title": "An Open-label, Multi-center, Phase I/II Study to Assess Safety, Tolerability and Efficacy of DFT383 in Pediatric Participants With Nephropathic Cystinosis, Followed by a Long-term Extension Phase",
  "first_posted_at": "2025-04-04T00:00:00.000Z"
}

{
  "url": "https://clinicaltrials.gov/study/NCT07733323",
  "title": "Respiratory Physiotherapy for Patients With Bronchiectasis",
  "nct_id": "NCT07733323",
  "phases": [],
  "source": "clinicaltrials.gov",
  "status": "ACTIVE_NOT_RECRUITING",
  "conditions": [
    "Bronchiectasis Adult"
  ],
  "enrollment": 270,
  "study_type": "OBSERVATIONAL",
  "lead_sponsor": "Yolanda Sanesteban Hermida",
  "published_at": "2026-07-29T00:00:00.000Z",
  "interventions": [],
  "sponsor_class": "OTHER",
  "official_title": "Analysis of the Profile of Patients Diagnosed With Bronchiectasis Referred to the Respiratory Physiotherapy Unit of the Rehabilitation Service in the A Coruña and Cee Health Area: a Retrospective Observational Study.",
  "first_posted_at": "2026-07-29T00:00:00.000Z"
}

{
  "url": "https://clinicaltrials.gov/study/NCT07415057",
  "title": "Simulation on the Enhancement of Clinical Communication Competencies in Nursing Students",
  "nct_id": "NCT07415057",
  "phases": [
    "NA"
  ],
  "source": "clinicaltrials.gov",
  "status": "NOT_YET_RECRUITING",
  "conditions": [
    "Communication"
  ],
  "enrollment": 50,
  "study_type": "INTERVENTIONAL",
  "lead_sponsor": "Escola Superior de Saúde Norte da Cruz Vermelha Portuguesa",
  "published_at": "2026-07-28T00:00:00.000Z",
  "interventions": [
    {
      "name": "Clinical Simulation",
      "type": "OTHER"
    }
  ],
  "sponsor_class": "OTHER",
  "official_title": "Effect of Simulation on the Enhancement of Clinical Communication Competencies in Nursing Students: Protocol for a Randomised Controlled Trial",
  "first_posted_at": "2026-02-17T00:00:00.000Z"
}

{
  "url": "https://clinicaltrials.gov/study/NCT00001177",
  "title": "Study of Premenstrual Syndrome and Premenstrual Dysphoria",
  "nct_id": "NCT00001177",
  "phases": [],
  "source": "clinicaltrials.gov",
  "status": "COMPLETED",
  "conditions": [
    "Mood Disorder"
  ],
  "enrollment": 1569,
  "study_type": "OBSERVATIONAL",
  "lead_sponsor": "National Institute of Mental Health (NIMH)",
  "published_at": "2026-07-28T00:00:00.000Z",
  "interventions": [],
  "sponsor_class": "NIH",
  "official_title": "The Evaluation of Women With Menstrually Regulated Mood and Behavioral Disorders",
  "first_posted_at": "1999-11-04T00:00:00.000Z"
}

{
  "url": "https://clinicaltrials.gov/study/NCT07731295",
  "title": "iPAWS: Improving Pain Management After Wisdom Tooth Extraction Surgery",
  "nct_id": "NCT07731295",
  "phases": [
    "NA"
  ],
  "source": "clinicaltrials.gov",
  "status": "RECRUITING",
  "conditions": [
    "Pain, Postoperative",
    "Substance Use"
  ],
  "enrollment": 150,
  "study_type": "INTERVENTIONAL",
  "lead_sponsor": "Brown University",
  "published_at": "2026-07-28T00:00:00.000Z",
  "interventions": [
    {
      "name": "iPAWS",
      "type": "BEHAVIORAL"
    },
    {
      "name": "Educational Materials",
      "type": "OTHER"
    }
  ],
  "sponsor_class": "OTHER",
  "official_title": "iPAWS: Improving Pain Management After Wisdom Tooth Extraction Surgery",
  "first_posted_at": "2026-07-28T00:00:00.000Z"
}

{
  "url": "https://clinicaltrials.gov/study/NCT02877394",
  "title": "Use of a Squatting Assist Device in Patients With Constipation",
  "nct_id": "NCT02877394",
  "phases": [
    "PHASE2"
  ],
  "source": "clinicaltrials.gov",
  "status": "ACTIVE_NOT_RECRUITING",
  "conditions": [
    "Constipation"
  ],
  "enrollment": 107,
  "study_type": "INTERVENTIONAL",
  "lead_sponsor": "Mayo Clinic",
  "published_at": "2026-07-28T00:00:00.000Z",
  "interventions": [
    {
      "name": "Squatting Assist Device",
      "type": "DEVICE"
    },
    {
      "name": "Sham Squatting Assist Device",
      "type": "DEVICE"
    }
  ],
  "sponsor_class": "OTHER",
  "official_title": "Use of a Squatting Assist Device in Patients With Constipation",
  "first_posted_at": "2016-08-24T00:00:00.000Z"
}