Clinical Trials

{
  "url": "https://clinicaltrials.gov/study/NCT07732790",
  "title": "Clinical Evaluation of Two Fissure Sealants (Resin Based Versus Giomer Fissure Sealants) on Molar Incisor Hypominerlisation Affected Permanent Molars (RCT)",
  "nct_id": "NCT07732790",
  "phases": [
    "NA"
  ],
  "source": "clinicaltrials.gov",
  "status": "COMPLETED",
  "conditions": [
    "Molar Hypomineralization, Incisor",
    "Fissure Sealant",
    "Resin Based Sealers"
  ],
  "enrollment": 22,
  "study_type": "INTERVENTIONAL",
  "lead_sponsor": "National Research Centre, Egypt",
  "published_at": "2026-07-29T00:00:00.000Z",
  "interventions": [
    {
      "name": "Resin based fissure sealant (Fisseal)",
      "type": "OTHER"
    },
    {
      "name": "Giomer based fissure sealant ( Beautisealant)",
      "type": "OTHER"
    }
  ],
  "sponsor_class": "OTHER",
  "official_title": "Clinical Evaluation of Resin Based Versus Giomer Fissure Sealants on MIH Affected Permanent Molars (RCT)",
  "first_posted_at": "2026-07-29T00:00:00.000Z"
}

{
  "url": "https://clinicaltrials.gov/study/NCT04323774",
  "title": "Intervention For Adolescents and Young Adults (AYAs) With Cancer Risk Syndromes",
  "nct_id": "NCT04323774",
  "phases": [
    "NA"
  ],
  "source": "clinicaltrials.gov",
  "status": "ACTIVE_NOT_RECRUITING",
  "conditions": [
    "Cancer Risk Syndrome"
  ],
  "enrollment": 115,
  "study_type": "INTERVENTIONAL",
  "lead_sponsor": "Dana-Farber Cancer Institute",
  "published_at": "2026-07-29T00:00:00.000Z",
  "interventions": [
    {
      "name": "AYA-RISE Adolescents and Young Adults Risk Information and Screening Education",
      "type": "BEHAVIORAL"
    },
    {
      "name": "Standard clinical visit for genetic counseling",
      "type": "BEHAVIORAL"
    }
  ],
  "sponsor_class": "OTHER",
  "official_title": "AYA-RISE: Refining a Scalable, Patient- and Family-centered Intervention to Improve Cancer Risk Communication and Decision-making Among Adolescents and Young Adults With Cancer Risk Syndromes",
  "first_posted_at": "2020-03-27T00:00:00.000Z"
}

{
  "url": "https://clinicaltrials.gov/study/NCT05896852",
  "title": "Healthy Lifestyles: A Home Based Physical Activity Intervention in Persons Living With HIV",
  "nct_id": "NCT05896852",
  "phases": [
    "NA"
  ],
  "source": "clinicaltrials.gov",
  "status": "COMPLETED",
  "conditions": [
    "HIV-1-infection",
    "Metabolic Syndrome"
  ],
  "enrollment": 40,
  "study_type": "INTERVENTIONAL",
  "lead_sponsor": "Georgetown University",
  "published_at": "2026-07-29T00:00:00.000Z",
  "interventions": [
    {
      "name": "physical activity",
      "type": "BEHAVIORAL"
    }
  ],
  "sponsor_class": "OTHER",
  "official_title": "Healthy Lifestyles: A Home Based Physical Activity Intervention in Persons Living With HIV",
  "first_posted_at": "2023-06-09T00:00:00.000Z"
}

{
  "url": "https://clinicaltrials.gov/study/NCT07734506",
  "title": "RELATIONSHIP BETWEEN ULTRASONOGRAPHIC QUADRICEPS MUSCLE THICKNESS AND SARCOPENIA MARKERS (HANDGRIP STRENGTH, SARC-F) AND KINESIOPHOBIA IN STROKE PATIENTS",
  "nct_id": "NCT07734506",
  "phases": [],
  "source": "clinicaltrials.gov",
  "status": "RECRUITING",
  "conditions": [
    "Stroke",
    "Sarcopenia",
    "Kinesiophobia"
  ],
  "enrollment": 50,
  "study_type": "OBSERVATIONAL",
  "lead_sponsor": "Istanbul Physical Medicine Rehabilitation Training and Research Hospital",
  "published_at": "2026-07-29T00:00:00.000Z",
  "interventions": [],
  "sponsor_class": "OTHER_GOV",
  "official_title": "EVALUATION OF THE RELATIONSHIP BETWEEN ULTRASONOGRAPHICALLY MEASURED QUADRICEPS MUSCLE THICKNESS AND SARCOPENIA MARKERS (HANDGRIP STRENGTH, SARC-F) AND KINESIOPHOBIA IN STROKE PATIENTS",
  "first_posted_at": "2026-07-29T00:00:00.000Z"
}

{
  "url": "https://clinicaltrials.gov/study/NCT04201106",
  "title": "A Neuroimaging Study of Open-label Placebo in Depressed Adolescents",
  "nct_id": "NCT04201106",
  "phases": [
    "NA"
  ],
  "source": "clinicaltrials.gov",
  "status": "TERMINATED",
  "conditions": [
    "Depression"
  ],
  "enrollment": 16,
  "study_type": "INTERVENTIONAL",
  "lead_sponsor": "University of California, San Francisco",
  "published_at": "2026-07-29T00:00:00.000Z",
  "interventions": [
    {
      "name": "Open Label Placebo with Rationale",
      "type": "BEHAVIORAL"
    },
    {
      "name": "Open Label Placebo without Rationale",
      "type": "BEHAVIORAL"
    }
  ],
  "sponsor_class": "OTHER",
  "official_title": "A Neuroimaging Study of Open-label Placebo in Depressed Adolescents",
  "first_posted_at": "2019-12-17T00:00:00.000Z"
}

{
  "url": "https://clinicaltrials.gov/study/NCT03005418",
  "title": "Humacyte Acellular Tissue Engineered Vessel (ATEV) in Patients With Vascular Trauma",
  "nct_id": "NCT03005418",
  "phases": [
    "PHASE2",
    "PHASE3"
  ],
  "source": "clinicaltrials.gov",
  "status": "COMPLETED",
  "conditions": [
    "Trauma",
    "Vascular System Injury"
  ],
  "enrollment": 72,
  "study_type": "INTERVENTIONAL",
  "lead_sponsor": "Humacyte, Inc.",
  "published_at": "2026-07-29T00:00:00.000Z",
  "interventions": [
    {
      "name": "Acellular Tissue Engineered Vessel (ATEV)",
      "type": "BIOLOGICAL"
    }
  ],
  "sponsor_class": "INDUSTRY",
  "official_title": "A Phase 2/3 Study for the Evaluation of Safety and Efficacy of Humacyte's ATEV for Vascular Replacement or Reconstruction in Patients With Life or Limb-threatening Vascular Trauma",
  "first_posted_at": "2016-12-29T00:00:00.000Z"
}

{
  "url": "https://clinicaltrials.gov/study/NCT04712318",
  "title": "Treatment of Residual Refraction Errors 6 Months After Trifocal IOL Implantation With Relex-Smile",
  "nct_id": "NCT04712318",
  "phases": [
    "NA"
  ],
  "source": "clinicaltrials.gov",
  "status": "ENROLLING_BY_INVITATION",
  "conditions": [
    "Pseudophakia",
    "Myopia",
    "Hyperopia"
  ],
  "enrollment": 130,
  "study_type": "INTERVENTIONAL",
  "lead_sponsor": "Eye Hospital Pristina Kosovo",
  "published_at": "2026-07-29T00:00:00.000Z",
  "interventions": [
    {
      "name": "Relex Smile",
      "type": "PROCEDURE"
    },
    {
      "name": "Relex smile with fresh corneal lenticule implantation",
      "type": "PROCEDURE"
    }
  ],
  "sponsor_class": "OTHER",
  "official_title": "Succesful Treatment of Residual Refraction Errors (Myopic and Hyperopic) 6 Months After Trifocal IOL Implantation With Relex-Smile",
  "first_posted_at": "2021-01-15T00:00:00.000Z"
}

{
  "url": "https://clinicaltrials.gov/study/NCT07378475",
  "title": "Evaluation of the Effectiveness of Manual Lymphatic Drainage in Young Women With Primary Dysmenorrhea",
  "nct_id": "NCT07378475",
  "phases": [
    "NA"
  ],
  "source": "clinicaltrials.gov",
  "status": "COMPLETED",
  "conditions": [
    "Dysmenorrhea Primary"
  ],
  "enrollment": 20,
  "study_type": "INTERVENTIONAL",
  "lead_sponsor": "Camilo Jose Cela University",
  "published_at": "2026-07-29T00:00:00.000Z",
  "interventions": [
    {
      "name": "Manual Lymphatic Drainage (MLD)",
      "type": "OTHER"
    }
  ],
  "sponsor_class": "OTHER",
  "official_title": "Evaluation of the Effectiveness of Manual Lymphatic Drainage in Young Women With Primary Dysmenorrhea",
  "first_posted_at": "2026-01-30T00:00:00.000Z"
}

{
  "url": "https://clinicaltrials.gov/study/NCT07732712",
  "title": "Isa-VRdlite for of Frail and/or Much Older Patients With High Risk Newly Diagnosed Multiple Myeloma Base on Circulating Plasma Cells",
  "nct_id": "NCT07732712",
  "phases": [
    "PHASE2",
    "PHASE3"
  ],
  "source": "clinicaltrials.gov",
  "status": "NOT_YET_RECRUITING",
  "conditions": [
    "Multiple Myeloma"
  ],
  "enrollment": 15,
  "study_type": "INTERVENTIONAL",
  "lead_sponsor": "The Affiliated People's Hospital of Ningbo University",
  "published_at": "2026-07-29T00:00:00.000Z",
  "interventions": [
    {
      "name": "Isatuximab",
      "type": "DRUG"
    },
    {
      "name": "VRD",
      "type": "DRUG"
    }
  ],
  "sponsor_class": "OTHER_GOV",
  "official_title": "Isa-VRdlite for of Frail and/or Much Older Patients With High Risk Newly Diagnosed Multiple Myeloma Base on Circulating Plasma Cells",
  "first_posted_at": "2026-07-29T00:00:00.000Z"
}

{
  "url": "https://clinicaltrials.gov/study/NCT07728175",
  "title": "Effects of Sirolimus on Asymptomatic ApoE4 Carriers",
  "nct_id": "NCT07728175",
  "phases": [
    "PHASE1"
  ],
  "source": "clinicaltrials.gov",
  "status": "NOT_YET_RECRUITING",
  "conditions": [
    "Genetic Predisposition to Disease",
    "Healthy Volunteer",
    "APOE-4 Positive"
  ],
  "enrollment": 225,
  "study_type": "INTERVENTIONAL",
  "lead_sponsor": "University of Missouri-Columbia",
  "published_at": "2026-07-29T00:00:00.000Z",
  "interventions": [
    {
      "name": "Sirolimus (rapamycin)",
      "type": "DRUG"
    },
    {
      "name": "Placebo",
      "type": "DRUG"
    }
  ],
  "sponsor_class": "OTHER",
  "official_title": "Effects of Sirolimus on Middle Aged Asymptomatic ApoE4 Carriers",
  "first_posted_at": "2026-07-27T00:00:00.000Z"
}