Clinical Trials

{
  "url": "https://clinicaltrials.gov/study/NCT07733141",
  "title": "Mindfulness Intervention to Reduce Patient Reported Symptoms in Patients With Chronic Graft-Versus-Host Disease",
  "nct_id": "NCT07733141",
  "phases": [
    "NA"
  ],
  "source": "clinicaltrials.gov",
  "status": "NOT_YET_RECRUITING",
  "conditions": [
    "Chronic Graft Versus Host Disease",
    "Hematopoietic and Lymphatic System Neoplasm",
    "Malignant Solid Neoplasm"
  ],
  "enrollment": 17,
  "study_type": "INTERVENTIONAL",
  "lead_sponsor": "City of Hope Medical Center",
  "published_at": "2026-07-29T00:00:00.000Z",
  "interventions": [
    {
      "name": "Biospecimen Collection",
      "type": "PROCEDURE"
    },
    {
      "name": "Mindfulness Relaxation",
      "type": "BEHAVIORAL"
    },
    {
      "name": "Mindfulness Relaxation",
      "type": "BEHAVIORAL"
    },
    {
      "name": "Mindfulness Relaxation",
      "type": "BEHAVIORAL"
    },
    {
      "name": "Survey Administration",
      "type": "OTHER"
    }
  ],
  "sponsor_class": "OTHER",
  "official_title": "Pilot Feasibility Study of Mindfulness-Based Intervention in Patients With Chronic Graft-Versus-Host Disease",
  "first_posted_at": "2026-07-29T00:00:00.000Z"
}

{
  "url": "https://clinicaltrials.gov/study/NCT06407427",
  "title": "Evaluating the Efficacy of a Mobile Application in Postoperative Rehabilitation",
  "nct_id": "NCT06407427",
  "phases": [
    "NA"
  ],
  "source": "clinicaltrials.gov",
  "status": "RECRUITING",
  "conditions": [
    "Spine Degeneration",
    "Hip Arthritis",
    "Knee Osteoarthritis",
    "Hip Fractures"
  ],
  "enrollment": 100,
  "study_type": "INTERVENTIONAL",
  "lead_sponsor": "Yale University",
  "published_at": "2026-07-29T00:00:00.000Z",
  "interventions": [
    {
      "name": "App for in-bed conditioning exercises",
      "type": "DEVICE"
    },
    {
      "name": "Usual care",
      "type": "OTHER"
    }
  ],
  "sponsor_class": "OTHER",
  "official_title": "Using a Mobile Application for In-Bed Conditioning Exercises for Orthopedic Postoperative Patients",
  "first_posted_at": "2024-05-09T00:00:00.000Z"
}

{
  "url": "https://clinicaltrials.gov/study/NCT06486441",
  "title": "Study of Sacituzumab Govitecan Versus Treatment of Physician's Choice in Participants With Endometrial Cancer After Platinum-Based Chemotherapy and Immunotherapy (ASCENT-GYN-01/GOG-3104/ENGOT-en26)",
  "nct_id": "NCT06486441",
  "phases": [
    "PHASE3"
  ],
  "source": "clinicaltrials.gov",
  "status": "ACTIVE_NOT_RECRUITING",
  "conditions": [
    "Endometrial Cancer"
  ],
  "enrollment": 640,
  "study_type": "INTERVENTIONAL",
  "lead_sponsor": "Gilead Sciences",
  "published_at": "2026-07-29T00:00:00.000Z",
  "interventions": [
    {
      "name": "Sacituzumab govitecan-hziy",
      "type": "DRUG"
    },
    {
      "name": "Doxorubicin",
      "type": "DRUG"
    },
    {
      "name": "Paclitaxel",
      "type": "DRUG"
    }
  ],
  "sponsor_class": "INDUSTRY",
  "official_title": "A Randomized, Open-label, Phase 3 Study of Sacituzumab Govitecan Versus Treatment of Physician's Choice in Participants With Endometrial Cancer Who Have Received Prior Platinum-based Chemotherapy and Anti-PD-1/PD-L1 Immunotherapy",
  "first_posted_at": "2024-07-03T00:00:00.000Z"
}

{
  "url": "https://clinicaltrials.gov/study/NCT07728773",
  "title": "A Stepped Intervention for Coping With Dyspnea in Patients With Lung Cancer-Phase A (Open Pilot)",
  "nct_id": "NCT07728773",
  "phases": [
    "NA"
  ],
  "source": "clinicaltrials.gov",
  "status": "NOT_YET_RECRUITING",
  "conditions": [
    "Dyspnea",
    "Lung Cancer (Diagnosis)"
  ],
  "enrollment": 10,
  "study_type": "INTERVENTIONAL",
  "lead_sponsor": "Massachusetts General Hospital",
  "published_at": "2026-07-29T00:00:00.000Z",
  "interventions": [
    {
      "name": "INSPIRE",
      "type": "BEHAVIORAL"
    }
  ],
  "sponsor_class": "OTHER",
  "official_title": "INSPIRE: A Stepped Intervention for Coping With Dyspnea in Patients With Lung Cancer-Phase A (Open Pilot)",
  "first_posted_at": "2026-07-27T00:00:00.000Z"
}

{
  "url": "https://clinicaltrials.gov/study/NCT05796388",
  "title": "A Study of Virtual Reality and Linaclotide for IBS-C",
  "nct_id": "NCT05796388",
  "phases": [
    "NA"
  ],
  "source": "clinicaltrials.gov",
  "status": "RECRUITING",
  "conditions": [
    "Irritable Bowel Syndrome With Constipation"
  ],
  "enrollment": 65,
  "study_type": "INTERVENTIONAL",
  "lead_sponsor": "Mayo Clinic",
  "published_at": "2026-07-29T00:00:00.000Z",
  "interventions": [
    {
      "name": "Virtual Reality",
      "type": "DEVICE"
    }
  ],
  "sponsor_class": "OTHER",
  "official_title": "A Pilot Study to Evaluate the Efficacy and Safety of Virtual Reality in Combination With Linaclotide for the Treatment of Adults With IBS and Constipation Predominance",
  "first_posted_at": "2023-04-03T00:00:00.000Z"
}

{
  "url": "https://clinicaltrials.gov/study/NCT06083883",
  "title": "Phase I/Ib Study of NK Expressing an Affinity-enhanced T-cell Receptor (TCR) Against the NY-ESO-1",
  "nct_id": "NCT06083883",
  "phases": [
    "PHASE1"
  ],
  "source": "clinicaltrials.gov",
  "status": "RECRUITING",
  "conditions": [
    "Synovial Sarcoma",
    "Myxoid/Round Cell Liposarcoma"
  ],
  "enrollment": 44,
  "study_type": "INTERVENTIONAL",
  "lead_sponsor": "M.D. Anderson Cancer Center",
  "published_at": "2026-07-29T00:00:00.000Z",
  "interventions": [
    {
      "name": "Fludarabine phosphate",
      "type": "DRUG"
    },
    {
      "name": "NY-ESO-1 TCR/IL-15 NK",
      "type": "DRUG"
    },
    {
      "name": "Cyclophosphamide",
      "type": "DRUG"
    }
  ],
  "sponsor_class": "OTHER",
  "official_title": "Phase I/Ib Study of Adoptive NK Expressing an Affinity-enhanced T-cell Receptor (TCR) Reactive Against the NY-ESO-1-specific Cord Blood-derived NK Cells (NY-ESO-1 TCR/IL-15 NK) in Conjunction With Lymphodepleting Chemotherapy for the Management of Advanced Synovial Sarcoma and Myxoid/Round Cell Liposarcoma",
  "first_posted_at": "2023-10-16T00:00:00.000Z"
}

{
  "url": "https://clinicaltrials.gov/study/NCT07015242",
  "title": "A Study of the Efficacy and Safety of Lisocabtagene Maraleucel (Liso-cel) as First-Line Therapy in Adults With Transplant-Ineligible Primary Central Nervous System Lymphoma",
  "nct_id": "NCT07015242",
  "phases": [
    "PHASE2"
  ],
  "source": "clinicaltrials.gov",
  "status": "RECRUITING",
  "conditions": [
    "Lymphoma"
  ],
  "enrollment": 65,
  "study_type": "INTERVENTIONAL",
  "lead_sponsor": "Juno Therapeutics, Inc., a Bristol-Myers Squibb Company",
  "published_at": "2026-07-29T00:00:00.000Z",
  "interventions": [
    {
      "name": "Rituximab",
      "type": "DRUG"
    },
    {
      "name": "Methotrexate",
      "type": "DRUG"
    },
    {
      "name": "Procarbazine",
      "type": "DRUG"
    },
    {
      "name": "Temozolomide",
      "type": "DRUG"
    },
    {
      "name": "Liso-cel",
      "type": "BIOLOGICAL"
    },
    {
      "name": "Fludarabine",
      "type": "DRUG"
    },
    {
      "name": "Cyclophosphamide",
      "type": "DRUG"
    },
    {
      "name": "Calcium folinate",
      "type": "DRUG"
    }
  ],
  "sponsor_class": "INDUSTRY",
  "official_title": "The CAROLYN Trial: Lisocabtagene Maraleucel as First-Line Therapy for Primary Central Nervous System Lymphoma (PCNSL) in Transplant-Ineligible Patients",
  "first_posted_at": "2025-06-11T00:00:00.000Z"
}

{
  "url": "https://clinicaltrials.gov/study/NCT06923280",
  "title": "Sequential PEG-IFN for HBV After Ending RNA-targeted Regimens",
  "nct_id": "NCT06923280",
  "phases": [
    "NA"
  ],
  "source": "clinicaltrials.gov",
  "status": "RECRUITING",
  "conditions": [
    "Hepatitis B, Chronic"
  ],
  "enrollment": 72,
  "study_type": "INTERVENTIONAL",
  "lead_sponsor": "Huashan Hospital",
  "published_at": "2026-07-29T00:00:00.000Z",
  "interventions": [
    {
      "name": "Pegylated Interferon-alpha (IFN)",
      "type": "DRUG"
    }
  ],
  "sponsor_class": "OTHER",
  "official_title": "Efficacy and Safety of Pegylated Interferon Therapy in Chronic Hepatitis B Patients After Discontinuation of Antisense Oligonucleotide or Small Interfering RNA: A Prospective, Adaptive, Open-label, Randomized Controlled Study",
  "first_posted_at": "2025-04-11T00:00:00.000Z"
}

{
  "url": "https://clinicaltrials.gov/study/NCT00341276",
  "title": "Esophageal Cancer Genetics Studies",
  "nct_id": "NCT00341276",
  "phases": [],
  "source": "clinicaltrials.gov",
  "status": "COMPLETED",
  "conditions": [
    "Esophageal Cancer",
    "Gastric (Cardia, Body) Cancer"
  ],
  "enrollment": 7705,
  "study_type": "OBSERVATIONAL",
  "lead_sponsor": "National Cancer Institute (NCI)",
  "published_at": "2026-07-29T00:00:00.000Z",
  "interventions": [],
  "sponsor_class": "NIH",
  "official_title": "Esophageal Cancer Genetics Studies",
  "first_posted_at": "2006-06-21T00:00:00.000Z"
}

{
  "url": "https://clinicaltrials.gov/study/NCT07732790",
  "title": "Clinical Evaluation of Two Fissure Sealants (Resin Based Versus Giomer Fissure Sealants) on Molar Incisor Hypominerlisation Affected Permanent Molars (RCT)",
  "nct_id": "NCT07732790",
  "phases": [
    "NA"
  ],
  "source": "clinicaltrials.gov",
  "status": "COMPLETED",
  "conditions": [
    "Molar Hypomineralization, Incisor",
    "Fissure Sealant",
    "Resin Based Sealers"
  ],
  "enrollment": 22,
  "study_type": "INTERVENTIONAL",
  "lead_sponsor": "National Research Centre, Egypt",
  "published_at": "2026-07-29T00:00:00.000Z",
  "interventions": [
    {
      "name": "Resin based fissure sealant (Fisseal)",
      "type": "OTHER"
    },
    {
      "name": "Giomer based fissure sealant ( Beautisealant)",
      "type": "OTHER"
    }
  ],
  "sponsor_class": "OTHER",
  "official_title": "Clinical Evaluation of Resin Based Versus Giomer Fissure Sealants on MIH Affected Permanent Molars (RCT)",
  "first_posted_at": "2026-07-29T00:00:00.000Z"
}