Clinical Trials

{
  "url": "https://clinicaltrials.gov/study/NCT04543097",
  "title": "Work And Vocational advicE Study - Effectiveness of Adding a Brief Vocational Support Intervention to Usual Primary Care",
  "nct_id": "NCT04543097",
  "phases": [
    "NA"
  ],
  "source": "clinicaltrials.gov",
  "status": "TERMINATED",
  "conditions": [
    "Musculoskeletal Pain",
    "Mental Health Issue",
    "Mental Health Disorder",
    "Other Physical Health Condition",
    "Absence"
  ],
  "enrollment": 130,
  "study_type": "INTERVENTIONAL",
  "lead_sponsor": "Keele University",
  "published_at": "2026-07-30T00:00:00.000Z",
  "interventions": [
    {
      "name": "Vocational Support",
      "type": "BEHAVIORAL"
    }
  ],
  "sponsor_class": "OTHER",
  "official_title": "Work And Vocational advicE (WAVE) in Primary Care: a Randomised Controlled Trial",
  "first_posted_at": "2020-09-09T00:00:00.000Z"
}

{
  "url": "https://clinicaltrials.gov/study/NCT02912559",
  "title": "Combination Chemotherapy With or Without Atezolizumab in Treating Patients With Stage III Colon Cancer and Deficient DNA Mismatch Repair",
  "nct_id": "NCT02912559",
  "phases": [
    "PHASE3"
  ],
  "source": "clinicaltrials.gov",
  "status": "ACTIVE_NOT_RECRUITING",
  "conditions": [
    "Colon Adenocarcinoma",
    "DNA Repair Disorder",
    "Lynch Syndrome",
    "Stage III Colon Cancer AJCC v8"
  ],
  "enrollment": 712,
  "study_type": "INTERVENTIONAL",
  "lead_sponsor": "National Cancer Institute (NCI)",
  "published_at": "2026-07-30T00:00:00.000Z",
  "interventions": [
    {
      "name": "Atezolizumab",
      "type": "DRUG"
    },
    {
      "name": "Biospecimen Collection",
      "type": "PROCEDURE"
    },
    {
      "name": "Computed Tomography",
      "type": "PROCEDURE"
    },
    {
      "name": "Fluorouracil",
      "type": "DRUG"
    },
    {
      "name": "Leucovorin Calcium",
      "type": "DRUG"
    },
    {
      "name": "Magnetic Resonance Imaging",
      "type": "PROCEDURE"
    },
    {
      "name": "Oxaliplatin",
      "type": "DRUG"
    },
    {
      "name": "Quality-of-Life Assessment",
      "type": "OTHER"
    }
  ],
  "sponsor_class": "NIH",
  "official_title": "Randomized Trial of Standard Chemotherapy Alone or Combined With Atezolizumab as Adjuvant Therapy for Patients With Stage III Colon Cancer and Deficient DNA Mismatch Repair",
  "first_posted_at": "2016-09-23T00:00:00.000Z"
}

{
  "url": "https://clinicaltrials.gov/study/NCT07737834",
  "title": "Clinical, Radiographic and Volumetric Evaluation of the Entire Papilla Preservation Technique With and Without Connective Tissue Graft in the Treatment of Periodontal Intraosseous Defects.",
  "nct_id": "NCT07737834",
  "phases": [
    "NA"
  ],
  "source": "clinicaltrials.gov",
  "status": "NOT_YET_RECRUITING",
  "conditions": [
    "Intrabony Periodontal Defect"
  ],
  "enrollment": 30,
  "study_type": "INTERVENTIONAL",
  "lead_sponsor": "Medical University of Warsaw",
  "published_at": "2026-07-30T00:00:00.000Z",
  "interventions": [
    {
      "name": "Entire Papilla Preservation Technique (EPPT)",
      "type": "PROCEDURE"
    },
    {
      "name": "EDTA root conditioning",
      "type": "OTHER"
    },
    {
      "name": "Enamel Matrix Derivative (EMD)- Emdogain",
      "type": "DRUG"
    },
    {
      "name": "Subepithelial Connective Tissue Graft (SCTG)",
      "type": "PROCEDURE"
    },
    {
      "name": "Bone substitute - Bio Oss Collagen",
      "type": "OTHER"
    }
  ],
  "sponsor_class": "OTHER",
  "official_title": "Clinical, Radiographic and Volumetric Evaluation of the Entire Papilla Preservation Technique With and Without Connective Tissue Graft in the Treatment of Periodontal Intraosseous Defects.",
  "first_posted_at": "2026-07-30T00:00:00.000Z"
}

{
  "url": "https://clinicaltrials.gov/study/NCT07032844",
  "title": "Advancing Diabetes Management for People With Physical Disabilities Optimally Through Primary Care-Based Telehealth (ADDOPT)",
  "nct_id": "NCT07032844",
  "phases": [
    "NA"
  ],
  "source": "clinicaltrials.gov",
  "status": "RECRUITING",
  "conditions": [
    "Type 2 Diabetes"
  ],
  "enrollment": 5000,
  "study_type": "INTERVENTIONAL",
  "lead_sponsor": "University of Alabama at Birmingham",
  "published_at": "2026-07-30T00:00:00.000Z",
  "interventions": [
    {
      "name": "Digital Health Coaching",
      "type": "BEHAVIORAL"
    },
    {
      "name": "Continuous Glucose Monitoring Teleconsults",
      "type": "BEHAVIORAL"
    },
    {
      "name": "Continuous Glucose Monitoring Teleconsults + Digital Health Coaching",
      "type": "BEHAVIORAL"
    }
  ],
  "sponsor_class": "OTHER",
  "official_title": "Comparing the Effectiveness of Primary Care Delivered Telehealth Interventions to Manage Type 2 Diabetes in People With Physical Disabilities and Multiple Chronic Conditions",
  "first_posted_at": "2025-06-24T00:00:00.000Z"
}

{
  "url": "https://clinicaltrials.gov/study/NCT07737236",
  "title": "Ruscus Evaluation for Symptom Control in Uncomplicated Chronic Venous Insufficiency",
  "nct_id": "NCT07737236",
  "phases": [],
  "source": "clinicaltrials.gov",
  "status": "RECRUITING",
  "conditions": [
    "Chronic Venous Disease"
  ],
  "enrollment": 564,
  "study_type": "OBSERVATIONAL",
  "lead_sponsor": "Turkish Society for Vascular and Endovascular Surgery",
  "published_at": "2026-07-30T00:00:00.000Z",
  "interventions": [],
  "sponsor_class": "OTHER",
  "official_title": "Evaluation of the Effects of Ruscus Aculeatus L. on Clinical Course and Quality of Life, and Assessment of Treatment Adherence and Tolerability in the Treatment of Chronic Venous Insufficiency: A Multicenter, Prospective, Observational Study",
  "first_posted_at": "2026-07-30T00:00:00.000Z"
}

{
  "url": "https://clinicaltrials.gov/study/NCT05665777",
  "title": "Chinese Medicine for Treating Chronic Pharyngolaryngitis",
  "nct_id": "NCT05665777",
  "phases": [
    "PHASE2"
  ],
  "source": "clinicaltrials.gov",
  "status": "RECRUITING",
  "conditions": [
    "Chronic Pharyngolaryngitis (Disorder)"
  ],
  "enrollment": 74,
  "study_type": "INTERVENTIONAL",
  "lead_sponsor": "Chinese University of Hong Kong",
  "published_at": "2026-07-30T00:00:00.000Z",
  "interventions": [
    {
      "name": "Qingyan Lihou Decoction",
      "type": "DRUG"
    },
    {
      "name": "Placebo",
      "type": "OTHER"
    }
  ],
  "sponsor_class": "OTHER",
  "official_title": "The Effectiveness and Safety of Qingyan Lihou Decoction for the Treatment of Chronic Pharyngolaryngitis: A Randomized, Double-blinded, Placebo-controlled Trial",
  "first_posted_at": "2022-12-27T00:00:00.000Z"
}

{
  "url": "https://clinicaltrials.gov/study/NCT05503225",
  "title": "Colchicine Use in Intracranial Atherosclerotic Disease",
  "nct_id": "NCT05503225",
  "phases": [
    "PHASE2"
  ],
  "source": "clinicaltrials.gov",
  "status": "RECRUITING",
  "conditions": [
    "ICAD - Intracranial Atherosclerotic Disease"
  ],
  "enrollment": 72,
  "study_type": "INTERVENTIONAL",
  "lead_sponsor": "Chinese University of Hong Kong",
  "published_at": "2026-07-30T00:00:00.000Z",
  "interventions": [
    {
      "name": "Colchicine 0.5 MG",
      "type": "DRUG"
    }
  ],
  "sponsor_class": "OTHER",
  "official_title": "Colchicine Use in Intracranial Atherosclerotic Disease - a Pilot Open-labelled Randomized Trial",
  "first_posted_at": "2022-08-16T00:00:00.000Z"
}

{
  "url": "https://clinicaltrials.gov/study/NCT06676059",
  "title": "SMART-r: Substance Monitoring and Active Relapse Tracking Repository",
  "nct_id": "NCT06676059",
  "phases": [],
  "source": "clinicaltrials.gov",
  "status": "RECRUITING",
  "conditions": [
    "Alcoholism",
    "Substance-Related Disorders"
  ],
  "enrollment": 10000,
  "study_type": "OBSERVATIONAL",
  "lead_sponsor": "National Institute on Drug Abuse (NIDA)",
  "published_at": "2026-07-30T00:00:00.000Z",
  "interventions": [],
  "sponsor_class": "NIH",
  "official_title": "SMART-r: Substance Monitoring and Active Relapse Tracking Repository",
  "first_posted_at": "2024-11-06T00:00:00.000Z"
}

{
  "url": "https://clinicaltrials.gov/study/NCT07725523",
  "title": "Safety and Efficacy of OTL78 (Zopocianine)",
  "nct_id": "NCT07725523",
  "phases": [
    "PHASE2",
    "PHASE3"
  ],
  "source": "clinicaltrials.gov",
  "status": "NOT_YET_RECRUITING",
  "conditions": [
    "Prostate Cancer Surgery",
    "Prostate Cancer Metastatic Disease"
  ],
  "enrollment": 36,
  "study_type": "INTERVENTIONAL",
  "lead_sponsor": "Clinton Bahler",
  "published_at": "2026-07-30T00:00:00.000Z",
  "interventions": [
    {
      "name": "0.06mg/kg ZOPOCIANINE given 1-7 days prior to surgery",
      "type": "DRUG"
    }
  ],
  "sponsor_class": "OTHER",
  "official_title": "Safety and Efficacy of OTL78 (Zopocianine), a Prostate-Specific Membrane Antigen (PSMA)-Targeted Fluorescent Agent, for Intraoperative Imaging of Prostate Cancer: A Phase IIb Trial",
  "first_posted_at": "2026-07-24T00:00:00.000Z"
}

{
  "url": "https://clinicaltrials.gov/study/NCT02465060",
  "title": "Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)",
  "nct_id": "NCT02465060",
  "phases": [
    "PHASE2"
  ],
  "source": "clinicaltrials.gov",
  "status": "ACTIVE_NOT_RECRUITING",
  "conditions": [
    "Advanced Lymphoma",
    "Advanced Malignant Solid Neoplasm",
    "Bladder Carcinoma",
    "Breast Carcinoma",
    "Cervical Carcinoma",
    "Colon Carcinoma",
    "Colorectal Carcinoma",
    "Endometrial Carcinoma",
    "Esophageal Carcinoma",
    "Exocrine Pancreas Carcinoma"
  ],
  "enrollment": 6452,
  "study_type": "INTERVENTIONAL",
  "lead_sponsor": "National Cancer Institute (NCI)",
  "published_at": "2026-07-30T00:00:00.000Z",
  "interventions": [
    {
      "name": "Adavosertib",
      "type": "DRUG"
    },
    {
      "name": "Afatinib",
      "type": "DRUG"
    },
    {
      "name": "Afatinib Dimaleate",
      "type": "DRUG"
    },
    {
      "name": "Binimetinib",
      "type": "DRUG"
    },
    {
      "name": "Biopsy Procedure",
      "type": "PROCEDURE"
    },
    {
      "name": "Biospecimen Collection",
      "type": "PROCEDURE"
    },
    {
      "name": "Capivasertib",
      "type": "DRUG"
    },
    {
      "name": "Computed Tomography",
      "type": "PROCEDURE"
    },
    {
      "name": "Copanlisib",
      "type": "DRUG"
    },
    {
      "name": "Copanlisib Hydrochloride",
      "type": "DRUG"
    }
  ],
  "sponsor_class": "NIH",
  "official_title": "Molecular Analysis for Therapy Choice (MATCH)",
  "first_posted_at": "2015-06-08T00:00:00.000Z"
}